Rule-based categorization deficits in focal basal ganglia lesion and Parkinson's disease patients

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Rule-based categorization deficits in focal basal ganglia lesion and Parkinson's disease patients.

Patients with basal ganglia (BG) pathology are consistently found to be impaired on rule-based category learning tasks in which learning is thought to depend upon the use of an explicit, hypothesis-guided strategy. The factors that influence this impairment remain unclear. Moreover, it remains unknown if the impairments observed in patients with degenerative disorders such as Parkinson's diseas...

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Parkinson's patients have been found to be impaired in learning movement sequences. In the current study, patients with unilateral basal ganglia lesions due to stroke were tested on a serial reaction time task in which responses were based on the spatial location of each stimulus. The spatial locations either followed a fixed sequence or were selected at random, with learning operationalized as...

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ژورنال

عنوان ژورنال: Neuropsychologia

سال: 2010

ISSN: 0028-3932

DOI: 10.1016/j.neuropsychologia.2010.06.006